Patient-reported outcome measures in adult HIV care: A rapid scoping review of targeted outcomes and instruments used

Objective
There is international interest in the integration of patient-reported outcome measures (PROMs) into routine HIV care, but little work has synthesized the content of published initiatives. We conducted a rapid scoping review primarily to identify their selected patient-reported outcomes and respective instruments.

Methods
Four databases were searched on 4 May 2022 (Medline, Embase, CINAHL and PsychINFO) for relevant English language documents published from 2005 onwards. Dual review of at least 20% of records, full texts and data extraction was performed. Outcomes and instruments were classified with an adapted 14-domain taxonomy. Instruments with evidence of validation were described.

Results
Of 13?062 records generated for review, we retained a final sample of 94 documents, referring to 60 distinct initiatives led mostly in the USA (n?=?29; 48% of initiatives), Europe (n?=?16; 27%) and Africa (n?=?9; 15%). The measured patient-reported outcome domains were: mental health (n?=?42; 70%), substance use (n?=?23; 38%), self-management (n?=?16; 27%), symptoms (n?=?12; 20%), sexual/reproductive health (n?=?12; 20%), physical health (n?=?9; 15%), treatment (n=?8; 13%), cognition (n?=?7; 12%), quality of life (n?=?7; 12%), violence/abuse (n?=?6; 10%), stigma (n?=?6; 10%), socioeconomic issues (n?=?5; 8%), social support (n?=?3; 5%) and body/facial appearance (n?=?1; 2%). Initiatives measured 2.6 outcome domains, on average (range?=?1–11). In total, 62 distinct validated PROMs were identified, with 53 initiatives (88%) employing at least one (M?=?2.2). Overwhelmingly, the most used instrument was any version of the Patient Health Questionnaire to measure symptoms of depression, employed by over a third (26; 43%) of initiatives.

Conclusion
Published PROM initiatives in HIV care have spanned 19 countries and disproportionately target mental health and substance use.

Contributors

Kim Engler, Francesco Avallone, Abdul Cadri, Bertrand Lebouché

Publication

Journal: HIV Medicine
Volume: 25
Issue: 6
Pages: 633 - 674
Year: 2024
DOI: 10.1111/hiv.13599

Further Study Information

Current Stage: Completed
Date:
Funding source(s):


Health Area

Disease Category: Infectious disease

Disease Name: HIV/AIDS

Target Population

Age Range: 18

Sex: Either

Nature of Intervention: Procedure

Stakeholders Involved

Study Type

- Systematic review of outcome measures/measurement instruments

Method(s)

- Systematic review