Core Outcome Measures in Effectiveness Trials

The COVER Project: Core Outcomes in Vascularized composite allotransplantation and Extremity Reconstruction

General Information

Summary:
The Core Outcomes in Vascularized composite allotransplantation and Extremity Reconstruction (COVER) Project aims to establish core outcomes for research in potential candidates for and recipients of vascularized composite allotransplantation and extremity reconstruction. Vascularized composite allotransplantation refers to the transplantation of multiple tissues such as muscle, bone, nerve and skin, as a functional unit (e.g. a hand, or face) from a deceased donor to a recipient with a severe injury. Extremity reconstruction may be necessary after trauma or cancer removal.

We will conduct systematic reviews, nominal group technique, Delphi Survey, Consensus workshops with relevant stakeholders to establish core outcome domains.

Contributors:
Hatem Amer, Mayo Clinic
Simon G Talbot, Harvard Medical School
Sheila Jowsey-Gregoire, Mayo Clinic
Allison Tong, The University of Sydney

Further Study Information

Current Stage:
Planning
Date:
November 2019 - November 2022
Funding source(s):
To be confirmed

Health Area

Disease Category
Other

Disease Name
Vascularized composite allotransplantation and extremity reconstruction

Target Population

Age Range
18 - 100

Sex
Either


Nature / type of Intervention
Surgery

Method(s)

Consensus conference
Consensus meeting
Focus group(s)
Interview
Literature review
Nominal group technique (NGT)
Semi structured discussion
Survey
Systematic review

We will conduct systematic reviews, nominal group technique, Delphi Survey, Consensus workshops with relevant stakeholders to establish core outcome domains.


Stakeholders Involved

Charities
Clinical experts
Conference participants
Consumers (caregivers)
Consumers (patients)
Device manufacturers
Economists
Epidemiologists
Ethicists
Families
Governmental agencies
Journal editors
Methodologists
Patient/ support group representatives
Pharmaceutical industry representatives
Policy makers
Regulatory agency representatives
Researchers
Service commissioners
Service providers
Service users
Statisticians

Study Type

COS for clinical trials or clinical research
COS for practice

The site uses cookies, some may have been set already. Please refer to our privacy policy & cookie usage statement.
If you continue to use the site we'll assume you're happy to accept the cookies.